PCOS: Getting Back To Good

I realize I haven’t posted about this in what feels like a while, and I guess the reason is because I have been in a bit of a holding pattern. After I had to stop taking the Serophene with two of five doses remaining, I had to wait to see if it had caused any follicles to mature and ovulate. After my vacation and the clinic’s vacation were over, I went in for cycle monitoring. There was no evidence of ovulation, nor were there any dominant follicles. It looked like besides the hot flashes and mood swings nothing had happened. Because of the eye issue that I had, which was why I didn’t finish my course of Serophene, and because three days on the highest dose they could offer showed no evidence of it working at all, they decided to start me on a new drug. But since I was so far into my cycle, it was best to flush my system and start fresh with a new cycle.

Provera (also known as Apo-Medroxy and the common name Medroxyprogesterone) is a progestin, basically a synthesized progesterone. Progesterone is the hormone that dominates the second half of a woman’s cycle, it prepares the uterine lining to nourish an embryo. In a normal woman who ovulates, the corpus luteum secretes progesterone, causing the level of this hormone to rise. Basal body temperature also rises. This is status quo for about 12-14 days or longer if an implanted embryo begins giving off hCG (the hormone detected in pregnancy tests). If there’s no hCG progesterone stops being produced, BBT drops, and the Crimson Tide (and a new cycle) commences. Provera, taken for ten days, mimics this progesterone rise without a corpus luteum and fools your body into thinking that ovulation happened but conception didn’t occur. So your brain hits ‘Reset’, and the Crimson Tide commences. And there’s your dose of science for the day.

Believe it or not, I hated biology before I started doing all this fertility stuff. Now finding out how this machine works is pretty cool!

So, I took Provera, and I took my last pill on Friday. By Sunday I was having wicked cramps, and it took until Wednesday for my new cycle to start. Provera periods can be pretty bad. They aren’t like normal periods. They’re a lot heavier and more painful… At least from my experience. This time around I think it also made me a lot more moody. I just keep telling myself that it’s temporary, and I can muscle through it. That said, there was a point today where it hurt do bad I was shaking from it. But! That’s why we have pain killers!

Today had to book all my appointments at the clinic. They are surprisingly busy right now, and they are squeezing me in to have my first cycle monitoring appointment on Monday (hopefully that will be when they put me on the Letrozole. Then I’ll be having another HSG and Sono done, one will be the very next day and the other will be on David‘s and my second wedding anniversary. How romantic?

I was feeling a little frustrated with all the waiting. I know it probably sounds crazy, but I really thought I’d be pregnant again by now. So sitting and waiting was not what I wanted to be doing. At least now I’m feeling like we’re getting back to good.

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